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Silico
Silico User Manual
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        • Run your first experiment
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        • Organize threads
        • Launch a plan
        • Monitor and steer
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        • Glossary
        • Restore cyber safety with internal probes
        • Prune a robot-control policy
        • Rerank protein–ligand poses

    Silico documentation

    Silico turns research questions into experiments and reports you can inspect, extend, and share.

    Watch the Silico product demo

    Get started

    1. 01Set upConnect the desktop app to your Lab.
    2. 02DefineTurn a question or paper into a testable experiment.
    3. 03ImproveLaunch the experiment and follow its Timeline.
    4. 04ValidateExplore the evidence and challenge the conclusion.
    5. 05IterateSteer, fork, or share the report with your team.

    Example reports

    See what a finished Silico report can look like.
    Restore cyber safety after preference tuning without losing helpfulness ↗ Model safety · Cybersecurity Preference tuning erodes cyber safety, and internal probes restore it Detect a hidden safety regression, then feed refusal and cyber-topic probes back into training to recover protection while preserving benign compliance. Slim down a robot-control policy without sacrificing task success ↗ Causal model design · Robotics Locate the causal interface before pruning it Find the layers a robot policy actually uses, then simplify its internal interface and test the leaner design on held-out tasks. Help a protein model find better drug-binding structures ↗ Model steering · Drug discovery A structure model's confidence score buries its own best answer Use hidden activations to surface promising protein–ligand structures the model ranked poorly, then steer it to generate more of them.